Published publications
- Laasfeld et al. 2026 – Kinetic assays to characterize fluorescent ligand binding to muscarinic acetylcholine M1 receptor
- Ullrich et al. 2025 – Discovery of a functionally selective serotonin receptor (5-HT1AR) agonist for the treatment of pain
- Laasfeld et al. 2025 – A bio. tools collection of online resources for GPCR research
- Ertl et al. 2024 – Dually Labeled Neurotensin NTS1R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays
- Allikalt et al. 2024 – MultiBacMam Technology for Studying the Downstream cAMP Signaling Pathway of M2 Muscarinic Acetylcholine Receptor
- Laasfeld et al. 2024 – Exploring Muscarinic Acetylcholine Receptor Binding Kinetics with Fluorescence Anisotropy
- Gleixner et al. 2024 – Illuminating Neuropeptide Y Y4 Receptor Binding: Fluorescent Cyclic Peptides with Subnanomolar Binding Affinity as Novel Molecular Tools
- Saar et al. 2023 – Exploring the Molecular Players behind the Potentiation of Chemotherapy Effects by Durvalumab in Lung Adenocarcinoma Cell Lines
- Tahk et al. 2023 – Fluorescence based HTS-compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
- Tahk et al. 2022 –
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses-which way to go with measuring ligand binding to M4 muscarinic receptors? - Ali et al. 2022 – ArtSeg—Artifact segmentation and removal in brightfield cell microscopy images without manual pixel-level annotations
- Lavõgina et al. 2022 – Revisiting the Resazurin‐Based Sensing of Cellular Viability: Widening the Application Horizon
- Müller et al.. 2022 – Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1Receptor
- Boritzki et al.. 2021 – Optimizing the Expression of Human Dopamine Receptors in Escherichia coli
- Lavõgina et al. 2021 – Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets
- Grätz et al. 2021 – BRET- and fluorescence anisotropy-based assays for real-time monitoring of ligand binding to M2 muscarinic acetylcholine receptors
- Laasfeld et al. 2021 – Budded baculoviruses as a receptor display system to quantify ligand binding with TIRF microscopy
- Veiksina et al. 2021 – Fluorescence Anisotropy-based Assay for Characterization of Ligand Binding Dynamics to GPCRs: The Case of Cy3B-Labeled Ligands Binding to MC4 Receptors in Budded Baculoviruses
- Fishman et al. 2021 – Practical segmentation of nuclei in brightfield cell images with neural networks trained on fluorescently labelled samples
- Lavõgina et al. 2021 – cAMP Biosensor Assay Using BacMam Expression System: Studying the Downstream Signaling of LH/hCG Receptor Activation
- Allikalt et al. 2020 – Fluorescent ligands for dopamine D2/D3 receptors
- Allikalt et al. 2020 – Quantitative analysis of fluorescent ligand binding to dopamine D3 receptors using live cell microscopy
- Link et al. 2019 – The constitutive activity of melanocortin-4 receptors in cAMP pathway is allosterically modulated by zinc and copper ions
- Allikalt et al. 2018 – Implementation of fluorescence anisotropy-based assay for the characterization of ligand binding to dopamine D1 receptors
- Mazina et al. 2017 – Determination of biological activity of gonadotropins hCG and FSH by Förster resonance energy transfer based biosensors
- Tekko et al. 2017 – Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors
- Allikalt, Rinken 2017 – Budded baculovirus particles as a source of membrane proteins for radioligand binding assay: The case of dopamine D1 receptor
- Sinijärv et al. 2017 – Binding assay for characterization of protein kinase inhibitors possessing sub-picomolar to sub-millimolar affinity
- Laasfeld et al. 2017 – Image-based cell-size estimation for baculovirus quantification
- Mazina et al. 2015 – cAMP Assay for GPCR Ligand Characterization: Application of BacMam Expression System
- Dzirkale et al. 2013 – Lunasin-induced behavioural effects in mice: focus on the dopaminergic system
Datasets
- Laasfeld et al. 2026 – UT-GPCR005 Fluorescence anisotropy time-series of competition binding between unlabeled ligands of M1 muscarinic acetylcholine receptor and TAMRA labeled UR-MK342
- Tahk et al. 2022 – UT-GPCR004 CHO-K1 cell line bright-field and fluorescence microscopy and corresponding segmentation ground truth
- Tahk et al. 2022 – UT-GPCR003 Fluorescence anisotropy and microscopy measurements experimental metadata of ligand binding to M4 muscarinic receptors
- Tahk et al. 2022 – UT-GPCR002 Machine learning models for CHO-K1 cell segmentation from fluorescence and bright-field microscopy images
- Tahk et al. 2022 – UT-GPCR001 microscopy of ligand binding to M4 muscarinic receptor in live CHO-K1-hM4 cells
- Ali et al. 2022 – ArtSeg-CHO-M4R: artifact segmentation in microscopy of ligand binding to M4 muscarinic receptor in live CHO-K1-hM4 cells